This 2020 study followed up The transgenerational impact of Roundup exposure using the Washington State Unversity research group’s most recent methodology in DEET and permethrin cause transgenerational diseases: “The herbicide glyphosate has been shown to promote epigenetic transgenerational inheritance of pathology and disease in subsequent great-grand offspring (F3 generation). The current study was designed to … Continue reading Part 2 of The transgenerational impact of Roundup exposure
This 2019 Washington rodent study from Dr. Michael Skinner’s lab found adverse effects in the grand-offspring and great-grand-offspring following their ancestor’s exposure during pregnancy to the world’s most commonly used herbicide: “Using a transient exposure of gestating F0 generation female rats found negligible impacts of glyphosate on the directly exposed F0 generation, or F1 generation … Continue reading The transgenerational impact of Roundup exposure
This 2018 French/Italian/Swiss rodent study was an extension of the work done by the group of researchers who performed Prenatal stress produces offspring who as adults have cognitive, emotional, and memory deficiencies and Treating prenatal stress-related disorders with an oxytocin receptor agonist: “Reduction of maternal behavior [nursing behavior, grooming, licking, carrying pups] was predictive of … Continue reading The lifelong impact of maternal postpartum behavior
This 2018 Canadian paper reviewed evidence for potential sex-specific differences in the lasting impacts of childhood trauma: “This paper will provide a contextualized summary of neuroendocrine, neuroimaging, and behavioral epigenetic studies on biological sex differences contributing to internalizing psychopathology, specifically posttraumatic stress disorder and depression, among adults with a history of childhood abuse. Given the … Continue reading Sex-specific impacts of childhood trauma
Was the recent Swiss avalanche’s cause the last, triggering snowflake, or the billions of snowflakes before it? There’s been a slight increase in the number of PNAS studies that included the “catastrophic” search word from October 2016 to mid-January 2018 compared to the January 2014 to mid-April 2015 period referenced in How well can catastrophes … Continue reading The impact of the last snowflake
Continuing with Dr. Arthur Janov’s May 2016 book Beyond Belief: “p. 17 When someone insults us, we immediately create reasons and rationales for it. We cover the pain. Now imagine a whole early childhood of insults and assaults and how that leaves a legacy that must be dealt with. The mind of ideas and philosophies … Continue reading Beyond Belief: The impact of merciless beatings on beliefs
This 2015 worldwide human study Hunger promotes acquisition of nonfood objects found that people’s current degree of hungriness affected their propensity to acquire nonfood items. The researchers admitted that they didn’t demonstrate cause and effect with the five experiments they performed, although the findings had merit. News articles poked good-natured fun at the findings with … Continue reading Do the impacts of early experiences of hunger affect our behavior, thoughts, and feelings today?
What I found curious in this 2012 UK review of 82 studies was the reviewer’s reluctance to highly regard a human’s life before birth, during infancy, and in early childhood. There was no lack in 2012 of animal studies to draw from to inferentially hypothesize how a human fetal environment causes the fetus to adapt … Continue reading Problematic research: Feigning naivety of the impact of prenatal, infancy and early childhood experiences
1. Per Improving healthy compounds of broccoli sprouts and Broccoli sprouts’ immune effects, this week I added mustard sprouts and red cabbage sprouts to my twice-daily routine of eating 3-day-old microwaved broccoli sprouts. At first, I started mustard and red cabbage seeds with the same 10.7 gram weight (one tablespoon) of seeds. They grew well … Continue reading Week 56 of Changing to a youthful phenotype with sprouts
This 2021 review subject was histone crotonylation: “Histone crotonylation is a newly identified epigenetic modification that has a pronounced ability to regulate gene expression. It belongs to an expanding group of short chain lysine acylations that also includes the extensively studied mark histone acetylation. Histone Kcr was first identified in 2011 where it was found … Continue reading An overlooked gut microbiota product
This 2021 review subject was probiotic bacteria survival and colonization: “Health benefits of probiotics are diminished due to substantial reduction of viable probiotic bacteria under harsh conditions in the gastrointestinal tract and colonization resistance caused by commensal bacteria. This review illustrates the journey of probiotics from oral administration to the gastrointestinal tract, followed by colonization … Continue reading Flailing with probiotics?
My 700th curation is a 2021 rodent study that investigated time-restricted prebiotic intake combined with an unrestricted bad diet: “Restricted prebiotic feeding during active phase induced weight-independent alleviation of liver steatosis and reduced serum cholesterol in high-fat diet (HFD) fed mice more significantly than unrestricted feeding. The prebiotic was a mixture of resistant starch [86%], … Continue reading Time-restricted prebiotics
Two 2021 reviews covered gut microbiota. The first was gut microbial origins of metabolites produced from our diets, and mutual effects: “Gut microbiota has emerged as a virtual endocrine organ, producing multiple compounds that maintain homeostasis and influence function of the human body. Host diets regulate composition of gut microbiota and microbiota-derived metabolites, which causes … Continue reading Treat your gut microbiota as one of your organs
This 2019 article was by the author of Sulforaphane: Its “Coming of Age” as a Clinically Relevant Nutraceutical in the Prevention and Treatment of Chronic Disease. It isn’t widely available, so I’ll quote liberally: “Demand for solutions to digestive health issues is accelerating, especially since both scientific literature and popular press dedicate significant resources to … Continue reading Harnessing endogenous defenses with broccoli sprouts
I came across this 2020 fiber-vs-fat rodent study from its citation in Gut microbiota and aging: “Dietary intervention studies largely revolve around altering fat content. Little consideration has been given to amount of fiber and whether or not it is soluble. We examined age- and sex-specific effects of a refined high-fat/low soluble fiber diet (rHFD) … Continue reading It’s the fiber, not the fat