The function of the dorsal ACC is to monitor pain in survival contexts

This 2015 California human study was of the dorsal anterior cingulate cortex (dACC): “No neural region has been associated with more conflicting accounts of its function than the dACC. The best psychological description of dACC function was related to pain processing—not executive, conflict, or salience processing. We conclude by considering that physical pain may be … Continue reading The function of the dorsal ACC is to monitor pain in survival contexts

Science and technology hijacked by woo

I’m an avid reader of science articles, abstracts, studies, and reviews. I tried a free subscription to Singularity Hub for a few weeks last month because it seemed to be a suitable source of articles on both science and technology. I unsubscribed after being disappointed by aspects of science and technology hijacked almost on a … Continue reading Science and technology hijacked by woo

How to cure the ultimate causes of migraines?

Most of the spam I get on this blog comes in as ersatz comments on The hypothalamus couples with the brainstem to cause migraines. I don’t know what it is about the post that attracts internet bots. The unwanted attention is too bad because the post represents a good personal illustration of “changes in the … Continue reading How to cure the ultimate causes of migraines?

Do preventive interventions for children of mentally ill parents work?

The fifth and final paper of Transgenerational epigenetic inheritance week was a 2017 German/Italian meta-analysis of psychiatric treatments involving human children: “The transgenerational transmission of mental disorders is one of the most significant causes of psychiatric morbidity. Several risk factors for children of parents with mental illness (COPMI) have been identified in numerous studies and meta-analyses. … Continue reading Do preventive interventions for children of mentally ill parents work?

A gaping hole in a review of nutritional psychiatry

This December 2016 Australian review published in September 2017 concerned: “..the nutritional psychiatry field..the neurobiological mechanisms likely modulated by diet, the use of dietary and nutraceutical interventions in mental disorders, and recommendations for further research.” The reviewers inexplicably omitted acetyl-L-carnitine, which I first covered in A common dietary supplement that has rapid and lasting antidepressant … Continue reading A gaping hole in a review of nutritional psychiatry

Beyond Belief: The impact of merciless beatings on beliefs

Continuing with Dr. Arthur Janov’s May 2016 book Beyond Belief: “p. 17 When someone insults us, we immediately create reasons and rationales for it. We cover the pain. Now imagine a whole early childhood of insults and assaults and how that leaves a legacy that must be dealt with. ..The mind of ideas and philosophies … Continue reading Beyond Belief: The impact of merciless beatings on beliefs

The hypothalamus couples with the brainstem to cause migraines

This 2016 German human study with one subject found: “The hypothalamus to be the primary generator of migraine attacks which, due to specific interactions with specific areas in the higher and lower brainstem, could alter the activity levels of the key regions of migraine pathophysiology.” The subject underwent daily fMRI scans, and procedures to evoke … Continue reading The hypothalamus couples with the brainstem to cause migraines

Genetic imprinting, sleep, and parent-offspring conflict

This 2016 Italian review subject was the interplay of genetic imprinting and sleep regulation: “Sleep results from the synergism between at least two major processes: a homeostatic regulatory mechanism that depends on the accumulation of the sleep drive during wakefulness, and a circadian self-sustained mechanism that sets the time for sleeping and waking throughout the … Continue reading Genetic imprinting, sleep, and parent-offspring conflict

Lack of oxygen’s epigenetic effects

This 2016 Finnish review’s subject was the epigenetic effects of hypoxia: “Ever since the Cambrian period, oxygen availability has been in the center of energy metabolism. Hypoxia stabilizes the expression of hypoxia-inducible transcription factor-1α (HIF-1α), which controls the expression of hundreds of survival genes related to enhanced energy metabolism and autophagy. There are several other … Continue reading Lack of oxygen’s epigenetic effects