Went to a free hearing test at Costco this week. Results weren’t significantly different than those from a doctor’s office 2.5 years ago:

Didn’t have many expectations, other than I’d be given a hard sell to buy hearing aids by a technician on commission. A young woman used several sales techniques which I was prepared for, and doubled down when I didn’t answer leading questions to her satisfaction.

The second study of Part 1 offered evidence that “The antioxidant pathway was difficult to be activated in the context of accumulation of ROS.” Other studies I’ve read but haven’t curated indicated that there weren’t effective treatments once hearing damage had occurred.

When you get exposed to loud noises, do your best to immediately mitigate that by enhancing your overall Nrf2 gene expression. Timely Nrf2 activation can fix hearing damage.

It’s curious that reactive oxygen species accumulated in the inner ear doesn’t sufficiently activate the Nrf2 there. That doesn’t happen in other parts of our or other mammals’ bodies.

I’ll guess that hearing loss may exist to turn old mammals into prey, as part of evolutionarily-determined limits on lifespan that protect against population overshoot. Take responsibility for your own one precious life.