Those of us who use painkillers rarely contemplate what pain it is that we’re targeting. For example, alcohol is a painkiller, but when we drink, do we focus on pain?
Detox centers work on the symptoms but seldom address the causes of the patient’s pain. Psychiatrists have no problem dispensing psychoactive medication for symptoms, but do have a problem dealing with the causes of the patient’s pain.
Painkillers can also kill us. This 2013 rodent study investigated “a potential therapeutic target for treatment of oxidative-stress related liver diseases” especially acetaminophen overdose.
Per one of this study’s references:
“Currently, the only clinically available treatment for acetaminophen overdose is N-acetyl-cysteine, a glutathione precursor, which has to be administered within 15–16 hours after acetaminophen ingestion to be effective.”
http://www.pnas.org/content/111/8/3176.full “TRPM2 channels mediate acetaminophen-induced liver damage”