From the main page of https://www.betaglucan.org/, a compilation for researchers:
“Beta Glucan extracted from yeast cell wall, can be a potent immune response potentiator and modulator. A common test to determine a glucan’s immune response potentiation effectiveness is the measure of the degree to which a glucan increases the nitric oxide burst, a pathogen killing agent.
Determinants of immune response activation and effectiveness are beta glucan source, processing, sizing and uniformity of beta glucan particles ingested. Particle size of 1-4 microns is optimum. Ingestion is optimized to prevent reaggregation.”
A sample of research:
“The tested (and suggested) daily dose remains in the range of 100–500 mg for stimulation of the immune system, whereas for a decrease in cholesterol levels a daily dose of 3 g is recommended.
Glucan supplementation prevents or even treats metabolic syndrome and decreases insulin resistance, dyslipidemia, and obesity. Glucan supplementation is a highly promising and inexpensive method of treatment for chronic respiratory problems.
Reactions known to be influenced by glucan are represented in white, reactions where glucan has no confirmed effects are shown in black.”
https://www.mdpi.com/1420-3049/24/7/1251/htm “Beta Glucan: Supplement or Drug? From Laboratory to Clinical Trials”
“Supplementation with glucan and vitamin D resulted in significant increase of vitamin D levels, improvements of HDL levels, and strong decrease of the total level of cholesterol.”
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897984/ “Effects of β-glucan and Vitamin D Supplementation on Inflammatory Parameters in Patients with Diabetic Retinopathy”
“β-glucan inhibits tumor growth through induced systemic tumor-antigen specific T cell response, increased activity of T-cells in tumor, and decreased number of tumor-caused immunosuppressive cells. Sulforaphane inhibits CRC [colorectal cancer] carcinogenesis by modulating Nrf2 activity and inhibition of HDAC enzymes.
In a women’s health initiative prospective cohort during their 11.7-year follow up of dietary fiber and omega-3, -6 fatty acids, the results pointed out a reduced incidence of CRC for the association between a low dose of soluble fiber, a high dose of insoluble fiber, and a high dose of EPA and DHA.”
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321468/ “Chemoprevention of Colorectal Cancer by Dietary Compounds”
I first curated the above review and graphic in Train your immune system every day! 12 days into a self-quarantine after coming back from Milano, Italy, Monday, February 24, 2020. There’s a substantial probability that my traveling companion and I were exposed to COVID-19.
Yet neither of us had any symptoms then or since. My β-glucan, Vitamin D3, and zinc amounts were the same as described in that post, in Take responsibility for your one precious life – Vitamin D3, and in Take responsibility for your one precious life – Zinc.