Eat whole oats for your gut microbiota

Two papers on whole grains, with the first a 2021 review: “Whole grains are more complex than refined grains and are promoted as part of a healthy and sustainable diet, mainly because the contribution of indigestible carbohydrates, and their co-passenger nutrients, is significantly higher. Changing composition and availability of grain carbohydrates and phytochemicals during processing … Continue reading Eat whole oats for your gut microbiota

Basal cognition

To follow up Electroceuticals, a 2021 article by Dr. Michael Levin: “A key philosophical idea, borrowed from computer science, is substrate independence. Components of a living system can carry out appropriate, clearly specified cognitive functions. Cognitive processes in embryogenesis and regeneration: (a) An egg will reliably give rise to a species-specific anatomical outcome. (b) This … Continue reading Basal cognition

Brown your white fat cells with broccoli sprouts

A 2021 rodent study and a blog post with 51 references investigated fat cells: “Sulforaphane (SFN) is a potent indirect antioxidant and a promising agent for controlling metabolic disorder disease. We evaluated efficacy of SFN against high fat diet (HFD)-induced-obesity mice, and investigated potential mechanisms. SFN: Suppressed HFD-induced body weight gain; Reduced fat cell [adipocyte] … Continue reading Brown your white fat cells with broccoli sprouts

Does sulforaphane treat autism?

A 2021 human study investigated sulforaphane treatments of autistic 3-to-12-year-olds: “Sulforaphane (SF) led to non-statistically significant changes in the total and all subscale scores of the primary outcome measure. Several effects of SF on biomarkers correlated to clinical improvements. SF was very well tolerated and safe and effective based on our secondary clinical measures. Clinical … Continue reading Does sulforaphane treat autism?

Eat broccoli sprouts instead of antibiotics

This 2020 cell study investigated antibiotic effects of broccoli sprout compounds: “In this work, we asked whether isothiocyanates (ITCs) could act synergistically with each other to increase antibacterial effect. A set of aliphatic ITCs, such as iberin, iberverin, alyssin, erucin, sulforaphene, erysolin, and cheirolin was tested in combination with sulforaphane against E. coli. All tested … Continue reading Eat broccoli sprouts instead of antibiotics

Giving children allergies with pets

This 2021 human study investigated development and persistence of allergies: “Allergic rhinitis (AR) is a common IgE-mediated disorder involving troublesome symptoms of nasal congestion, nasal itch, sneezing, and associated eye symptoms. Like many chronic health conditions, AR stems from complex gene–environment interactions. 130 subjects with AR were recruited. Control population included 154 healthy children who … Continue reading Giving children allergies with pets

Week 56 of Changing to a youthful phenotype with sprouts

1. Per Improving healthy compounds of broccoli sprouts and Broccoli sprouts’ immune effects, this week I added mustard sprouts and red cabbage sprouts to my twice-daily routine of eating 3-day-old microwaved broccoli sprouts. At first, I started mustard and red cabbage seeds with the same 10.7 gram weight (one tablespoon) of seeds. They grew well … Continue reading Week 56 of Changing to a youthful phenotype with sprouts

Eat broccoli sprouts for your heart

This 2021 rodent study investigated mechanisms of sulforaphane’s persistent cardiac protection: “Sulforaphane (SFN) reduced Ang II‐induced CpG hypermethylation and promoted Ac‐H3 [histone H3 acetylation] accumulation in the Nrf2 promoter region, accompanied by inhibition of global DNMT [DNA methyltransferase] and HDAC [histone deacetylase] activity, and a decreased protein expression of key DNMT and HDAC enzymes. Overall, … Continue reading Eat broccoli sprouts for your heart

Year One of Changing to a youthful phenotype with broccoli sprouts

1. My subjective experiences these past 52 weeks are that noticeable changes keep happening due to combinations of: Eating clinically-relevant, twice-daily doses of microwaved 3-day-old broccoli sprouts, and taking nothing else an hour before or an hour after; Eating 3-day-old oat sprouts twice a day; Exercising every day; Taking yeast cell wall β-glucan and other … Continue reading Year One of Changing to a youthful phenotype with broccoli sprouts

Our first 1000 days

This 2021 review subject was a measurable aspect of our early lives: “The first 1000 days from conception are a sensitive period for human development programming. During this period, environmental exposures may result in long-lasting epigenetic imprints that contribute to future developmental trajectories. The present review reports on effects of adverse and protective environmental conditions … Continue reading Our first 1000 days

Week 50 of Changing to a youthful phenotype with broccoli sprouts

1. Effects of broccoli sprouts that seemed personally astounding at Week 10 became a part of day-to-day life. What will happen next? Day 350 of eating a clinically relevant amount of broccoli sprouts every day seems like a large number. Yet in comparison, for 6,000+ days I’ve taken a clinically relevant dose of 1/3, 1/6 … Continue reading Week 50 of Changing to a youthful phenotype with broccoli sprouts

Hooray for the People of Texas!

One anecdote from “vacationing” in the Dallas area last week: I waited until temperatures were above 15° F to forage for food. The closest grocery store had the same situation as my hotel: no electricity all morning. It somehow had electricity for cash registers, but not for overhead lighting. People walked around using their phone’s … Continue reading Hooray for the People of Texas!

Adaptive and innate immunity

Two 2021 reviews presented aspects of human immune systems: “The adaptive immune system’s challenge is to protect the host through generation and differentiation of pathogen‐specific short‐lived effector T cells, while in parallel developing long‐lived memory cells to control future encounters with the same pathogen. The system highly relies on self‐renewal of naïve and memory T … Continue reading Adaptive and innate immunity

Part 2 of Eat broccoli sprouts for DIM

Continuing Part 1 with three DIM studies, the first of which was a 2020 chemical analysis investigating: “Anti-estrogenic, anti-androgenic, and aryl hydrocarbon receptor (AhR) agonistic activities of indole-3-carbinol (I3C) acid condensation products. I3C is a breakdown product [isothiocyanate] of glucobrassicin. Most biological activities attributed to I3C are believed to result from its acid condensation products, … Continue reading Part 2 of Eat broccoli sprouts for DIM