This 2015 human summary study was of 44 genetic disorders that disrupt the maintenance of epigenetic modifications: “..making them likely to have significant downstream epigenetic consequences. Interestingly, these patients often demonstrate neurological dysfunction, suggesting that precise epigenetic regulation may be critical for neuronal homeostasis. However, at the same time, it is important to keep in … Continue reading Genetic causes for epigenetic symptoms
This 2015 New York rodent study provided further details on the production of new neurons in the adult hippocampus. The researchers found that a protein that regulated a glutamate receptor also: “Significantly influences hippocampal neurogenesis and that both the proliferation and survival of newborn neurons are impaired in the absence.” The study showed: “The effect … Continue reading Another factor in producing new brain neurons in the adult hippocampus
This 2015 La Jolla rodent study provided further details on the production of new neurons in the adult hippocampus: “We propose that SOX2 sets a permissive epigenetic state in neural progenitor cells, thus enabling proper activation of the neuronal differentiation program under neurogenic cue.” The researchers stated that the functions of these new brain neurons … Continue reading Epigenetic production of new brain neurons in the hippocampus
This 2014 rodent study found that fat cells released a certain hormone during exercise that produced two beneficial effects: the hormone increased hippocampal neurogenesis; it also reduced depression-like behaviors. So if you’re feeling kinda blue, Think your brain cells are too few? Get your fat cells on that bike and ride! http://www.pnas.org/content/111/44/15810.full “Physical exercise-induced hippocampal … Continue reading Are you feeling kinda blue? Think your brain cells are too few? Get your fat cells on that bike and ride!