This 2015 Chicago review noted: “Recent developments in the research of ASD [autistic spectrum disorder] with a focus on epigenetic pathways as a complement to current genetic screening. Not all children with a predisposing genotype develop ASD. This suggests that additional environmental factors likely interact with the genome in producing ASD. Increased risk of ASD … Continue reading A review of genetic and epigenetic approaches to autism
This 2015 Swedish rodent study found: “Women with polycystic ovary syndrome (PCOS) display high circulating androgen levels that may affect the fetus and increase the risk of mood disorders in offspring. Although clinical data are inconsistent, there are indications that androgens play a crucial role in behavior and mood regulation in females. Studies on the … Continue reading Fetal exposure to sex hormones and female anxiety
This 2015 Northwestern University rodent study found: “Fear-inducing memories can be state dependent, meaning that they can best be retrieved if the brain states at encoding and retrieval are similar. Memories formed in a particular mood, arousal or drug-induced state can best be retrieved when the brain is back in that state. “It’s difficult for … Continue reading A study that provided evidence for basic principles of Primal Therapy
This 2015 UK rodent study provided details of how neurons in the hippocampus respond to stimuli. The researchers found that hippocampal neurons: “Remain electrically stable when confronted with chronic increases in neuronal activity.” Changes in electrical potential changed the initial segment of the neuron’s axon. Synapses formed along the segment, and stayed in place while … Continue reading How brain neurons remain stable when constantly stimulated
This joint 2015 Australian/German rodent study found that oxytocin bound to the brain receptors that cause loss of motor control with alcohol intoxication, and prevented rats from displaying these symptoms: “While oxytocin might reduce your level of intoxication, it won’t actually change your blood alcohol level,” Dr Bowen said. “This is because the oxytocin is … Continue reading Oxytocin blocks alcohol intoxication symptoms
This 2014 rodent research reliably induced many disorders common to humans. Here are some post-birth problems the researchers caused, primarily by applying different types of stress, as detailed in the study’s supplementary material: Social defeat Social avoidance behavior Learned helplessness Irritable bowel syndrome Depression Anxiety Anhedonia Yet the researchers’ goal was to identify a brain … Continue reading If research provides evidence for the causes of stress-related disorders, why only focus on treating the symptoms?
This 2014 rodent study was of polycystic ovarian syndrome, which is the leading cause of human female infertility. The researchers could reliably induce this disease in mice while they were still fetuses, but effects didn’t manifest until adulthood! The inducement method exposed the developing female fetuses to androgens such that their testosterone concentration was significantly … Continue reading Sex hormone exposure to the developing female fetus causes infertility in adulthood