Eat oats and regain cognitive normalcy

This 2020 rodent study investigated effects of different diets: “The present study aimed to evaluate effects of β-glucan on the microbiota gut-brain axis and cognitive function in an obese mouse model induced by a high-fat and fiber-deficient diet (HFFD). After long-term supplementation for 15 weeks, β-glucan prevented HFFD-induced cognitive impairment, assessed behaviorally by object location, novel … Continue reading Eat oats and regain cognitive normalcy

Pigs and glucosinolates

This 2020 porcine study subject was improving healthy aspects of canola-oil-processing by-products: “We hypothesized that inclusion of high-amylose cornstarch (HA-starch) in canola co-products-based diets for pigs can reduce hindgut pH, leading to increased degradation of glucosinolates present in hindgut of pigs into non-goitrogenic products. Most dietary myrosinases [enzymes] are inactivated by heat during cooking, pressing … Continue reading Pigs and glucosinolates

Let β-glucan train your brain

This 2021 rodent study investigated yeast cell wall β-glucan’s effects on the brain’s immune system: “Innate immune memory can manifest in two different ways, [1] immune training and [2] immune tolerance, which means [1] an enhanced or [2] suppressed immune response towards a secondary challenge. Lipopolysaccharide (LPS) and β-glucan (BG) are two commonly used ligands … Continue reading Let β-glucan train your brain

Oat β-glucan effects on colitis

This 2021 rodent study investigated oat β-glucan effects on colitis: “In this study, we determined effects of consumption of low- and high-molar-mass oat beta-glucans on expression of selected markers of apoptosis and autophagy in colonocytes in TNBS colitis-induced rats. We analyzed expression of colon wall receptors, including TLRs and Dectin-1, which are involved in recognition … Continue reading Oat β-glucan effects on colitis

Year One of Changing to a youthful phenotype with broccoli sprouts

1. My subjective experiences these past 52 weeks are that noticeable changes keep happening due to combinations of: Eating clinically-relevant, twice-daily doses of microwaved 3-day-old broccoli sprouts, and taking nothing else an hour before or an hour after; Eating 3-day-old oat sprouts twice a day; Exercising every day; Taking yeast cell wall β-glucan and other … Continue reading Year One of Changing to a youthful phenotype with broccoli sprouts

Evaluating a company-sponsored β-glucan paper

This 2020 review subject was yeast cell wall β-glucan effects in humans: “The first aim of this review is to collate and interpret the existing pre‐clinical research on β‐1,3/1,6‐glucan with regard to immunity in order to clarify its molecular mechanism of immunomodulatory action. The second aim of this review is to collate and evaluate the … Continue reading Evaluating a company-sponsored β-glucan paper

Choosing your future with β-glucan

This 2020 rodent study investigated yeast cell wall β-glucan effects on bacterial infections: “β-glucan is a potent inducer of epigenetic and functional reprogramming of innate immune cells, a process called trained immunity, resulting in an enhanced host response against secondary infections. We investigate whether β-glucan exposure confers protection against pulmonary Mycobacterium tuberculosis (Mtb) infection. β-glucan … Continue reading Choosing your future with β-glucan

β-glucan comparisons

This 2018 rodent study compared and contrasted commercially available β-glucans: “β-glucans are natural biologically-active compounds called ‘biological response modifiers.’ This study is a follow-up of our three previous studies that tested 43 different glucans. We used 16 different glucans isolated from yeasts, mushrooms, algae, and oats. We compared their effects on phagocytosis, IL-2 production, antibody … Continue reading β-glucan comparisons

Oat digestibility

A reader questioned one part of Oat species comparisons of the good stuff regarding Avena nuda hull digestibility. This 2019 study partially investigated that aspect: “We investigated effects of proteins, lipids, and β-glucan in naked oat flour on in vitro digestibility of starch. Content of rapidly digested starch increased, and content of resistant starch decreased … Continue reading Oat digestibility

Oat species comparisons of the good stuff

This 2020 study compared and contrasted distributional compositions of two oat species’ seeds: “Oat grains of one hulless variety (Lamont) with low avenanthramide (AVA) contents and one hulled variety (Reins) with high AVA contents were sequentially abraded. Contents of nutrients (protein, oil, starch, β-glucan, ash, and other carbohydrates) and AVAs were measured. A relationship between … Continue reading Oat species comparisons of the good stuff

Long-lasting benefits of a common vaccine

This 2021 review subject was effects of the 100-year-old tuberculosis vaccine: “Bacillus Calmette-Guerin (BCG) vaccine is one of the most widely used vaccines. It protects against many non-mycobacterial infections secondary to its nonspecific immune effects. The mechanism for these effects includes modification of innate and adaptive immunity. BCG vaccine is known to not only boost … Continue reading Long-lasting benefits of a common vaccine

Week 50 of Changing to a youthful phenotype with broccoli sprouts

1. Effects of broccoli sprouts that seemed personally astounding at Week 10 became a part of day-to-day life. What will happen next? Day 350 of eating a clinically relevant amount of broccoli sprouts every day seems like a large number. Yet in comparison, for 6,000+ days I’ve taken a clinically relevant dose of 1/3, 1/6 … Continue reading Week 50 of Changing to a youthful phenotype with broccoli sprouts

Eat oats to prevent diabetes

This 2020 rodent study investigated Type 2 diabetics eating oats along with a bad diet: “Type 2 diabetes (T2D) is a metabolic disease which is characterized by a state of chronic low-grade inflammation with abnormal expression and production of multiple inflammatory mediators. Insulin resistance (IR), a condition where higher-than-normal concentration of insulin is needed to … Continue reading Eat oats to prevent diabetes

Sprouting hulless oats

I finished a 3-lb. bag of hulled Avena sativa oats used in Sprouting hulled oats after starting 20 gram batches twice a day. Amazon said that Montana farmer’s products were “Currently unavailable. We don’t know when or if this item will be back in stock.” I went to their website and emailed an inquiry. Turns … Continue reading Sprouting hulless oats