This 2021 in vitro study examined butyrate producers: “Butyrate produced by gut microbiota has multiple beneficial effects on host health. Oligosaccharides derived from host diets, and glycans originating from host mucus, are major sources of its production. Butyrate is the major energy source for epithelial cells in the distal colon, induces differentiation of colonic regulatory … Continue reading Every baby needs a sugar mama
While getting ready for bed tonight, I mused about how my younger brother had such an idealized postmortem view of our father. As he expressed six years ago in an obituary for our high school Literature teacher: “I’ll remember my favorite teacher and how much he’s meant to my life. My father and Martin Obrentz … Continue reading We believe what we need to believe
Yesterday’s team meeting at work provided one display after another of a person’s need to feel important. These eye-openers were the reason the scheduled 30-minute meeting lasted 45 minutes. Although half of the forty or so attendees are under the age of 40, curiously, only two of them spoke during the meeting. I wasn’t among … Continue reading Your need to feel important will run your life, and you’ll never feel satisfied
A coauthor of the studies referenced in: Advance science by including emotion in research; and Empathy, value, pain, control: Psychological functions of the human striatum offered an opinion piece in A Paper a Day Keeps the Scientist Okay entitled “Do We Need To Study The Brain To Understand The Mind?” “The emerging consensus appears to … Continue reading Do we need to study the brain to understand the mind?
A magazine article New Clues to How the Brain Maps Time reviewed the findings of a 2015 Boston rodent study During Running in Place, Grid Cells Integrate Elapsed Time and Distance Run. The article’s information was mixed such that when the reader arrived at this phrase: “Moreover, time cells rely on context; they only mark … Continue reading Publicly-funded researchers need to provide unqualified free access to their studies
This 2014 wild chimpanzee study demonstrated how necessary it was to have a mother’s “nourishment, transportation, warmth, protection, and socialization,” in other words, a mother’s love, during infancy and early childhood. http://www.pnas.org/content/111/51/18189.full “Early social exposure in wild chimpanzees: Mothers with sons are more gregarious than mothers with daughters”
This 2022 cell study investigated yeast cell wall β-glucan’s effects on angiogenesis: “Angiogenesis, the formation of new blood vessels, is essential for embryonic development and physiological damage repair, such as wound healing and post-ischemic tissue restoration. It is also essential for pathological processes, such as diabetic retinopathy, rheumatoid arthritis, and atherosclerosis. We evaluated physical and … Continue reading Take β-glucan for new blood vessels
Haven’t curated a study for a while that actually detracted from science. This 2022 human clinical trial that polluted broccoli sprout compounds research provoked me into it: “Forty-nine participants enrolled, including 26 (53%) females with median use of 20 cigarettes/day. Low and higher-dose broccoli seed and sprout extracts (BSSE) showed a mean bioavailability of 11% … Continue reading Unconscious act-outs all the way down
Two papers, starting with a 2022 abstract of an ongoing in vitro study with rodent cells: “Exercise mimetics may target and activate the same mechanisms that are upregulated with exercise administration alone. This is particularly useful under conditions where contractile activity is compromised due to muscle disuse, disease, or aging. Sulforaphane and Urolithin A represent … Continue reading Exercise substitutes?
A follow-on to Beginning of the cure for aging: “So, I rubbed a small sample of E5 on my right hand and after three days the results were visible. The skin on the treated hand is visibly thicker and lighter. Certainly not a definitive test, but wow, my hand looks decades younger. Dr. Harold Katcher … Continue reading Reinvigorated
Two papers on oat compounds’ bioavailability, starting with a 2022 review: “There are many nutrients and bioactive chemical compounds exerting beneficial properties in oats. Results indicated that oats and their extracts possessed essential roles in preventing chronic diseases. However, most studies focused on Avns’ [avenanthramides] functions were performed using cell models. In animal models, one … Continue reading Estimating bioavailability of oat compounds
I’ll highlight this 2021 human study’s findings regarding stress: “We profiled hair pigmentation patterns (HPPs) along individual human hair shafts, producing quantifiable physical timescales of rapid greying transitions. White/grey hairs that naturally regain pigmentation across sex, ethnicities, ages, and body regions, quantitatively define reversibility of greying in humans. A systematic survey of two-colored hairs on … Continue reading Reversing hair greying
Two papers on Vitamin K, beginning with a 2021 review: “Vitamin K is involved in many biological processes. Menaquinones (MK) [Vitamin K2] and phylloquinone [Vitamin K1] vary in biological activity, showing different bioavailability, half-life, and transport mechanisms. The effective dose to decrease uncarboxylated osteocalcin was six times lower for MK-7 than for MK-4. Similarly, MK-7 … Continue reading Vitamin K forms
Here are three papers that cited last year’s Part 1. First is a 2021 rodent study investigating a microRNA’s pro-depressive effects: “Depressive rat models were established via chronic unpredicted mild stress (CUMS) treatment. Cognitive function of rats was assessed by a series of behavioral tests. Nrf2 was weakly expressed in CUMS-treated rats, whereas Nrf2 upregulation … Continue reading Eat broccoli sprouts for depression, Part 2
This 2022 review suggested more effective ways to conduct in vitro studies of advanced glycation end products (AGEs) and neurodegenerative diseases: “The main goal of this review was to present and discuss in vitro models that were applied or have the potential to be used in research on AGEs and ND. We introduced and explained … Continue reading Studying AGEs and neurodegeneration