Search Results for: need

Your need to feel important will run your life, and you’ll never feel satisfied

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Yesterday’s team meeting at work provided one display after another of a person’s need to feel important. These eye-openers were the reason the scheduled 30-minute meeting lasted 45 minutes. Although half of the forty or so attendees are under the age of 40, curiously, only two of them spoke during the meeting. I wasn’t among … Continue reading Your need to feel important will run your life, and you’ll never feel satisfied

Do we need to study the brain to understand the mind?

gettingwell4 4-5 stars Advanced knowledge, Amygdala, Anterior cingulate cortex, Cerebrum, Hippocampus, Limbic system, Memory

A coauthor of the studies referenced in: Advance science by including emotion in research; and Empathy, value, pain, control: Psychological functions of the human striatum offered an opinion piece in A Paper a Day Keeps the Scientist Okay entitled “Do We Need To Study The Brain To Understand The Mind?”: “The emerging consensus appears to … Continue reading Do we need to study the brain to understand the mind?

Publicly-funded researchers need to provide unqualified free access to their studies

gettingwell4 0-1 star Wasted resources, Hippocampus, Limbic system, Memory

A magazine article New Clues to How the Brain Maps Time reviewed the findings of a 2015 Boston rodent study During Running in Place, Grid Cells Integrate Elapsed Time and Distance Run. The article’s information was mixed such that when the reader arrived at this phrase: “Moreover, time cells rely on context; they only mark … Continue reading Publicly-funded researchers need to provide unqualified free access to their studies

The need for a mother’s love

gettingwell4 4-5 stars Advanced knowledge, Brain development

This 2014 wild chimpanzee study demonstrated how necessary it was to have a mother’s “nourishment, transportation, warmth, protection, and socialization,” in other words, a mother’s love, during infancy and early childhood. http://www.pnas.org/content/111/51/18189.full “Early social exposure in wild chimpanzees: Mothers with sons are more gregarious than mothers with daughters”

Statistical inferences vs. biological realities

gettingwell4 2-3 stars Needed further work, Epigenetics, Immune system, Memory, Stress, Telomeres , , ,

A 2019 UCLA study introduced a derivative of the epigenetic clock named GrimAge: “DNAm GrimAge, a linear combination of chronological age, sex, and DNAm-based surrogate biomarkers for seven plasma proteins and smoking pack-years, outperforms all other DNAm-based biomarkers, on a variety of health-related metrics. An age-adjusted version of DNAm GrimAge, which can be regarded as … Continue reading Statistical inferences vs. biological realities

A therapy to reverse cognitive decline

gettingwell4 4-5 stars Advanced knowledge, Cerebrum, Cortisol, Hippocampus, Immune system, Limbic system, Memory, Neurochemicals, Stress, Telomeres, Testosterone , , , , , ,

This 2018 human study presented the results of 100 patients’ personalized therapies for cognitive decline: “The first examples of reversal of cognitive decline in Alzheimer’s disease and the pre-Alzheimer’s disease conditions MCI (Mild Cognitive Impairment) and SCI (Subjective Cognitive Impairment) have recently been published..showing sustained subjective and objective improvement in cognition, using a comprehensive, precision … Continue reading A therapy to reverse cognitive decline

Epigenetic transgenerational inheritance mechanisms that lead to prostate disease

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This 2019 Washington rodent study found: “Ancestral exposure to the toxicant vinclozolin induces an epigenetic transgenerational increase in susceptibility to prostate pathology in F3 [male great-grandchildren] generation rats. These results are in agreement with previous studies which found a transgenerational increase in rates of prostatic epithelial atrophy, cystic hyperplasia, and prostatitis in the transgenerational F3 … Continue reading Epigenetic transgenerational inheritance mechanisms that lead to prostate disease

Epigenetic causes of sexual orientation and handedness?

gettingwell4 2-3 stars Needed further work, Brain development, Brain hemispheres, Cerebrum, Epigenetics, Testosterone , , , , , , , ,

This 2018 Austrian human study subject was various associations of prenatal testosterone levels to fetal development: “The available evidence suggests, albeit not conclusively, that prenatal testosterone levels may be one cause for the association of sexual orientation with handedness. Associations among women were consistent with predictions of the Geschwind–Galaburda theory (GGT), whereas those among men … Continue reading Epigenetic causes of sexual orientation and handedness?

Burying human transgenerational epigenetic evidence

gettingwell4 < 0 Detracted from science, Beliefs, Cerebrum, Epigenetics , , ,

The poor substitutes for evidence in this 2018 US study guaranteed that human transgenerational epigenetically inherited effects wouldn’t be found in the generations that followed after prenatal diethylstilbestrol (DES) exposure: “A synthetic, nonsteroidal estrogen, DES was administered to pregnant women under the mistaken belief it would reduce pregnancy complications and losses. From the late 1930s … Continue reading Burying human transgenerational epigenetic evidence

A slanted view of the epigenetic clock

gettingwell4 2-3 stars Needed further work, Epigenetics ,

The founder of the epigenetic clock technique was interviewed for MIT Technology Review: “We need to find ways to keep people healthier longer,” he says. He hopes that refinements to his clock will soon make it precise enough to reflect changes in lifestyle and behavior.” The journalist attempted to dumb the subject down “for the … Continue reading A slanted view of the epigenetic clock